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About me

Hi, I'm Natalie.

Cancer researcher, teacher, and incoming PhD student at Oxford University. I study cancer at the molecular level and believe that rigorous science and genuine human care are not opposites, but the same thing.

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Natalie Sorensen

How my story unfolds

Uncertainty is cold. It seeps in slowly, first numbing, then isolating, until everything familiar feels foreign. I first felt it the night my mother told us she had cancer. The walls of our home, once steady and warm, felt suddenly brittle. I did not understand much about the disease, but I understood that everything was about to change.

Our household had always been one built on determination. My father taught himself to code and became a software engineer, despite never completing a formal education. My mother, who grew up in public housing and never went to college, was the emotional anchor of our home. But when illness took hold, the roles each of us held shifted. My older brother became the constant chaperone for me and my younger sibling. I became a sous-chef, preparing meals. My mother became a student in her own illness, her own nutritionist, and most importantly, focused on recovering.

For as long as I can remember, I have had a quiet fascination with science and the human body. I dissected bugs in the backyard and watched surgical procedures on TV when no one was watching, drawn to what others found uncomfortable. But when my mother was diagnosed, that scattered curiosity quickly became resolute. I was desperate to push back against the cold weight of uncertainty, so I began researching her cancer. Suddenly, all I wanted was to be part of the effort to unravel the complexities of human health.

My parents were able to cover only my first semester of college. After that, I worked multiple jobs while carrying a full course load, determined to finish in three years and avoid the cost of a fourth. Along the way, I chose leadership roles where I learned how to build trust, guide others, and grow as both a student and a future scientist.

At first, I was not sure I belonged in science. I had no research experience, no connections, and no clear path forward. Instead, I created my own opportunity. I took a non-research job just to place myself near the work I was eager to do. Eventually, I earned a spot in a lab studying immune responses to prosthetic debris. There, I learned foundational techniques including flow cytometry, cell culture, and antibody staining, while collaborating across multiple labs. When the project stalled due to delays beyond my control, I did not question my place. Instead, I saw the broader lesson: science does not just require technical skill. It requires confidence, adaptability, and resilience.

That mindset carried me to graduate school at San Francisco State University and into research at UCSF, where I study osteosarcoma. Using techniques such as CUT&RUN and single-cell multiomics, I investigate how transcription factor networks drive tumor behavior. Each experiment reinforces what I once only dreamed: that I am not just capable of this work, I am meant for it.

That feeling grew stronger when I began shadowing a pediatric oncologist. I watched her move through patient visits with warmth and precision, remembering where a patient had applied to college, and then gently pacing follow-up scans so they could enter their next stage of life without medical procedures overshadowing it. In her, I saw what I hoped to become: someone who brings both intellect and warmth to spaces that often feel cold and clinical.

On my first day shadowing, I met a young man. He was 24 years old and dying. His parents were not ready to let go, so he endured agonizing pain just to give them a little more time together. There was no more treatment to offer, no experimental drug to try, no scan that would change the course. Science had run out. What mattered most in that moment was how his physicians showed up: present, honest, and patient enough to hold space for both clinical reality and compassion.

That experience reshaped how I see medicine. While science gives us tools, medicine is defined by how we support people in the absence of answers. I want to become a surgeon-scientist because I want to help design better questions, not just for experiments, but for people.

"You can't ever reach perfection, but you can believe in an asymptote toward which you are ceaselessly striving." Paul Kalanithi

This idea captures what draws me to cancer research. We may never fully solve diseases like cancer, but with every experiment, every failure, and every incremental advance, we move closer to understanding and closer to offering patients more time, more options, and more hope.

I have been accepted to Oxford's Phd program in oncology, where I will study colon cancer, one of the most prevalent and rapidly rising cancers worldwide. This opportunity represents more than academic progress. It reflects how far persistence and purpose can carry a person.

After completing my PhD, I plan to attend medical school in the United States, so I can give back not only through research but through direct patient care and community outreach. My long-term goal is to run clinical trials and experimental treatments as a surgeon-scientist, improving outcomes and quality of life for patients directly.

Research gives me a way to find clarity. Medicine gives me a way to offer warmth where the world feels coldest. I am ready to do both.

Teaching and mentorship

The part of this work
that keeps me grounded.

Research can feel abstract. Teaching never does. Every student I have worked with has reminded me why the science matters in the first place.

Anatomy with real stakes
Teaching cadaver-based anatomy labs is unlike anything else. Students walk in nervous and walk out with a completely different relationship to the human body. Guiding that shift, and watching someone understand for the first time how a structure they have read about actually sits in space, is one of the most rewarding things I do.
What tutoring taught me about learning
Privately tutoring biology and chemistry forced me to understand not just the material, but how different people get stuck on it. Watching the moment a concept clicks for someone who had convinced themselves they were not a science person changed how I think about teaching entirely. Most people are not bad at science. They just have not had it explained in a way that makes sense to them.
Access as a form of mentorship
Through SEES outreach and peer mentoring, I worked with students who were capable and motivated but operating without the same network others take for granted. The most meaningful thing I could offer was not always content knowledge. It was visibility into what was possible, and someone in their corner who believed they belonged in these spaces.
The long game

Where I'm headed and why it matters.

🔬

PhD at Oxford in oncology

Three years studying colon cancer at the molecular level at one of the world's leading oncology research institutions. Colon cancer is the 3rd most common cancer globally and the 2nd leading cause of cancer death, with rising rates in adults under 50.

🏥;

Medical school in the United States

After the PhD, I plan to attend medical school in the US. I want to give back not only through research, but through direct patient care and community outreach. The MD and PhD together are the most powerful combination I can bring to the people I want to serve.

🧬

Surgeon-scientist and clinical trials

My long-term goal is to run clinical trials and experimental treatments as a surgeon-scientist, improving outcomes and quality of life for patients directly. I want to sit at the intersection of discovery and care, where the science I do can reach the people who need it most.

🌍

Teaching, mentorship, and access

Throughout everything, I will keep teaching and mentoring. The students I have worked with remind me why this matters beyond the lab. Teaching at a college and making myself accessible as a future physician are goals I take as seriously as my research career.

Background

Education, honors and research

Education

PhD in Oncology, Oxford University

Accepted, starting 2026

MS in Biomedical Science, Stem Cell Science

San Francisco State University, 2024 to 2026

BS in Biology

Cal Poly Pomona, 2021 to 2024 (completed in 3 years)

Honors and Awards

Agents of Change SF Build Fellow

2026

SFSU CIRM Stem Cell Research Scholar

2025

NSF SPIRES Scholar

2023 to 2024

Louis Stokes Alliance for Minority Participation Scholar

2023 to 2024

Research Experience

Research Assistant, UCSF Pediatric Oncology Lab

January 2025 to present, Mission Bay, CA

Undergraduate Researcher, Dr. Alas Lab, Cal Poly Pomona

2023 to 2024. Immune responses to prosthetic debris; flow cytometry, cell culture, phagocytic assays

Publications and Presentations

Cancer Discovery, 2025

Lopez-Fuentes, Clugston, Lee, Sayles, Sorensen et al. Epigenetic and transcriptional programs define osteosarcoma subtypes.

View publication

Poster, CIRM Conference 2025

"Chromatin Accessibility and Transcription Factor Networks in Osteosarcoma," Los Angeles, CA

Key Techniques

Genomics and Epigenomics

ATAC-seq, RNA-seq, CUT&RUN, single-cell multiome, TapeStation

Molecular and Cellular

Western blot, IHC, immunofluorescence, FACS/flow cytometry, PCR, cell culture

In Vivo

PDX mouse models, orthotopic implantation, IVIS imaging, limb amputation, dissection

Outside of the lab

You can usually catch me in a garden, enjoying some art, or looking for funny looking animals. I recently got a pair of binoculars to help!

Exploring an art garden
Natalie hiking the Havasupai trail
Hiking the Havasupai trail
Natalie fascinated by a meerkat
Life and all its creatures fascinate me
Ready to help?

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Questions? fundnatalie@sorensn.com